Bivalirudin Organic Chemicals CAS 128270-60-0

• Customization: Available
• CAS No.: 128270-60-0
• Formula: C98h138n24o33
• Model NO.: Bivalirudin
• Classification: High Purity Material
• Grade: LR
• Specific Usage: For Biological Purpose, Technical Grade
• Content: Standard
• Usage: Laboratory Reagents, Analytical Reagents
• Source: Dry Powder
• Habit Appellation: Chemical Medicine
• Application: Industry, Scientific Research
• Storage Environment: Low Temperature Drying
• Shelf Life: 3 Years
• MW: 358.21
• Transport Package: 1kg/Bag
• Specification: 1000kg
• Trademark: Star-Selection
• Origin: Huanggang
• HS Code: 000000
• Production Capacity: 100000kg/Year

Product Description

 

Product Description

 

 

 

Product name	Bivalirudin
Appearance	White powder
CAS NO.	128270-60-0
MF	C98H138N24O33
MW	2180.317

Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.

 

Function of Bivalirudin CAS 128270-60-0
 

1. It can significantly reduce the incidence of bleeding in elective PCI patients. The total clinical outcome risk fell 14%.
2. It does not cause antibody-mediated thrombocytopenia.
3. Reversibly bind with thrombin. Short half-life. Hard to develop ischemic and hemorrhagic complications.
4. It is not mainly excreted through the kidneys and can be safely used in patients with renal impairment.

 

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